In CodeIgniter, the application flow chart typically follows these steps:
1. **Index.php**: The entry point of the application.
2. **Bootstrap**: Loads the framework and initializes the application.
3. **Routing**: The URI is parsed to determine the controller and method to call.
4. **Controller**: The specified controller is instantiated.
5. **Model**: If needed, the controller interacts with the model to retrieve or manipulate data.
6. **View**: The controller loads the appropriate view to display the output.
7. **Output**: The final output is sent to the browser.
This flow ensures a structured approach to handling requests and responses in a CodeIgniter application.