Typical usages of middleware in Django include:
1. Request and response processing (e.g., modifying requests/responses).
2. Session management (e.g., handling user sessions).
3. User authentication and authorization (e.g., checking user permissions).
4. Cross-Site Request Forgery (CSRF) protection.
5. Content Gzipping for performance optimization.
6. Logging and monitoring requests and responses.
7. Handling exceptions and errors globally.